About two hours ago I did the Cole quest and had no issues whatsoever :/
I hadn't had any real CtD issues since Patch 2-or-so, until Patch 10/Trespasser. The game became almost unplayable with repeatable crashes during combat, and most annoyingly, cutscene transitions (e.g. for Cole's PQ).
Tried many of the suggestions I'd seen on various forums, including playing in "Windowed mode" and reducing graphics to LOW, but what worked for me was removing the "Lunge-n-Slash" ability from every Warrior. (Note that this was successful even though there is no combat, and I had no Warrior's in the "party" when resolving Cole's PQ. Weird, huh?)
Not a solution, just a work-around, but at least I can continue with the playthrough!
I'll see if I can maneuver around this. Cheers for this possible help!
And I, too, had absolutely no issues with DA:I save the banter bug (which is still too long a wait... but I digress) and even after getting a new, awesome graphics card a few months ago? No hiccups.
Then this! I mean it's more of an annoyance seeming it doesn't screw up my PC and make me have to force close it... but it's bloody annoying!