No fan-pandering meme-spouting in the game and no sit-com interactions a la DA:I this time.
I wanted to puke going through the companion stuff in the Trespasser DLC because they kept going the sit-com route with comedy. Lots of missing animation cues, sounds and overall pathetic attempt to be funny was (obviously) not fun to see.
Take your story seriously, and use comedic relief properly e.g. with characters cracking some jokes, occasional camp and tongue-in-cheek dialogue but don't resort to memes or fan-pandering humor like "haha, calibrations, blahblha, garrus, blahblah calibrations haha" like in ME3. Way to kill immersion in a series that I feel is made to be immersive.
DA:I was an all-new low. Citadel DLC I can accept because it's a DLC specifically for campy fan-pandering meme and player-requested moments on top of a really disappointing main-story finale, but that's an exception. DA:I had no excuse for being so cringe-inducing throughout its core game or epilogue DLC. If you're gonna break the tone of your narrative at least don't do it as part of the story or a gap in the story where you have companion interaction. I don't want ME:A's normandy crew conversations to be filled with bad jokes Bioware took directly from reddit's Mass Effect page.