I don't think there's any way BioWare could realistically create an engaging, diverse, and integral colonization mechanic. Just think about how many 4X games have this many choices with regards to colonization, and those are games that are both exclusively devoted to such mechanics and aren't required to make full renders of these cities. Every other game with this mechanic on the side has failed to make it any better than a somewhat repetitive and ultimately meaningless set of side-quests. BioWare is a good developer, but I don't have faith that they could revolutionize colonization.
Moreover, I don't really want BioWare to take this route. So many games (so. many. games.) these days are pushing the colonization/zone control mechanic to the point where I don't want to see it anymore even if it makes perfect sense to have it. Game companies are aggressively pushing this absurd power fantasy that we, the player, the chosen one, the only person in this static world that apparently has any semblance of agency, need to control everything. It's as if every subsequent game needs to one-up the progression system of the previous one. It's simply gotten to the point of absurdity.
So I don't want BioWare to go anywhere near colony management, partly because I'm certain that it would just be another ho-hum side mechanic that isn't fully fleshed out and feels out of place when juxtaposed with the rest of the game, but mainly because I'm tired of being told the same old power-grab story told from the same "avatar of universe" perspective.