I avoid swearing in my day to day life to the point that some of my friends tease me for it, but I love lots of movies with a high profanity quotient. Most of them are by Guy Ritchie or Quentin Tarantino.
I'd be all for either of them working on one of these games, and I have absolutely no issue with the inclusion of whatever profanity the writers put in, but there is something to be said for making up fake swear words in a science fiction setting. For one thing, it avoids the issue of regional variations and the slight problem of having people so far into the future using the exact same common swear words that we use today.
Some of today's english "bad" words are still rooted in the old british class system. It stretches plausibillity if the way society in a setting centuries ahead of ours treats language exactly the same.
On the other hand, made up slang/swearing can easily come off as hokey. I read one futuristic series where characters said something was "frosty," instead of cool, and "mag," instead of fabulous. It didn't make the dialogue very smooth.
Firefly did pretty well with all the chinese swearing.