Oh, Seattle. I lived there for five years, though tbh didn't really see the sights much since I was too busy studying and working.
WARNING: I'm a nerd so the only stuff I know are museums and such.
1.) There's a coffee shop every five feet. Seattle's got ya covered.
2.) There's the Space Needle. It's got a restaurant at the top. 'Course this time of year you'll get an awesome view of gray rainy clouds instead of the cool view of the city skyline framed by Mount Rainier.
3.) If you're interested in museums, music, or sci fi there's the EMP Museum. Cool place.
4.) Lots of pilots in my family so I'm kind of an aviation nut, and always enjoyed the Museum of Flight. It's got mostly planes and some space vehicles. No mako yet, unfortunately.
5.) The Underground Tour if you like historical type things.
Now if you ask me about bars or night spots i'll just stare at you blankly. Restaurants, well, kinda clueless there too aside from the space needle since I never eat out much. Seattle supposedly has seafood but I'm a nerdy vegetarian so dunno there.
also Palaven aka Eastern Washington where I live is located ~200 miles to the East of Seattle so you can face that direction once you arrive in Seattle and wave and I'll wave back.
edit: If your conference is at the UW Med School or something you can go out on the campus, find the fountain, and jump in the horrible dirty water to commemorate a very dumb thing I did during college. If not disregard.
edit2: then again if you do this and take a picture of yourself doing it I reward you with a million .... bsn bucks