.... I feel ME is forgetting about the far out science that made it seem like such a unique thing.
Edited: In a lot of sci-fi stories ... few of them explain their own techno babble, whether it be founded in real science or not. [Most story writers) ... assume we understand or not make it a focal point for the story, yet ME didn't do that. The ME series to me made me think that their science was possible in their universe. EDI...sets up the idea that the universe isn't exactly like ours and that their science works different than ours - but that it's still a science and they clearly understand it and explain it to us the players.
I don't think there is enough information at this time to determine whether ME:A "is forgetting about the science that made it seem like such a unique thing (in the original trilogy)."
You are absolutely correct that Sci-Fi stories can rely on techno-babble (and glitzy special effects) to impress us and mask over a weak story that is short on intelligent explanation for new science and tech. The cutscene in the earliest stages showing Shepard's resurrection in ME-2 was the simple visual demonstration of how this was accomplished internally, basically through injections of chemicals and micro-implant repairs. Although there clearly wasn't a full explanation of the new science used by Cerberus to accomplish this feat, we were at least given a visualization of the process to make it plausible (in a fantasy world), rather than simply being told that 'it happened.' That segment treated us in a way to draw us in, to visually see something happening. I didn't need to be told that they used artificial sweeteners, Polysorbate 80, dimethyl cellulose, and stabilizing agents to control the chemical reactions. We were given a brief visual and that was all I needed to move on.
The other thing that ME did well in the Sci-fi genre is give us characters that were likeable, and with plausible development of their personal backgrounds and history. No easy task. And like Star Trek original series, TNG, DS9, Voyager, and Battle Star Galactica, the interpersonal relationships and conversations between the characters were interesting enough and used inside humor that we can understand - we get it; these are aspects that make the characters more real - and trusted. I don't think BW is going to forget about these crucial elements in story and character development in a rpg - as opposed to games where the only thing that matters is driving, senseless gratuitous violent behavior and blood-lust.
I have faith that the writers have the experience to write a full-bodied story that is intelligent.
Sci-fi stories that address and make me think about the issues and basic qualities of being human, and what makes an entity sentient, really grab my attention and make me think about the deeper fundamental concepts. In ST: TNG, Data had an episode where he created a genderless android 'child' who selected her gender and race (human), and her name Lal (not an ambiguous name like Pat!). The episode was titled "The Offspring." Though we are only told that it/she was developed using "submicron matrix transfer technology" - which isn't explained at all, the technical description uses terms that we, as Sci-fi and technology fans, can relate to - it wasn't completely new techno-babble. It was good enough. And watching Hallie Todd make such an amazing performance, and the issues of sentience, creating a slave race, and freedom of choice to determine one's own future, is so engaging that I didn't care to have "submicron matrix transfer technology" fully explained. Would it be useful to have a NPC character in ME:A with identity concerns, such as "What/who am I ?; What will I become? " - I think so, and perhaps in dealing with a LI relationship (edit: ...where conversations can delve into and explore the more personal aspects of a person's life and viewpoints).
Edit: For example, Paragon Shepard worked with Ashley over time in ME-1 to help her see that aliens can be allies who can be trusted. Given her life's limited background and experiences with her father and grandfather, she needed to have more experience in an alien-filled galaxy that she didn't know too well. I felt her initial caution regarding aliens (it wasn't racism) was understandable given her experiences. And I'm really glad that the story showed an evolution in her perspectives. The trope that a person's attitudes can grow and evolve over the course of a journey is a very good thing to see, so long as it is isn't trying to force the observer to agree with a particular political/social agenda.
The 'open world' concept worries me a bit more, and I fear about getting miserably lost and being in a galaxy that isn't filled in.