Are we supposed to be looking for a new permanent home world for the races of our galaxy?
What species would want to completely abandon the home planet and not eventually try and come back and reclaim it?
I'm assuming that this crew knows what it's signing up for, that their orders are to do nothing that could possibly attract the Reapers' attention, and that the trip will take so long that there's no guarantee that the state of the Milky Way would be anything they'd even recognize any more if they did try to go back.
If they want to completely abandon ME3 and the logic they have established so far if we find that organic life is abundant and Andromeda is not overrun with synthetics/hybrids I suppose the only way to rationalise that would be that the Reapers were wrong about Destroy and Control ultimately leading to (slaughter or a zha'til esque) disaster after-all but I guess we'll have to wait and see.
I've figured all along that the Catalyst is probably wrong. Some of its operating premises were likely pre-programmed by the Leviathans, who don't exactly have the most objective point of view on these things, and its conclusions are seemingly based partly on observing organic-synthetic interactions only as they played out under the Leviathans' dominance over the galaxy. The Catalyst is a good example of what can go wrong if you create an AI with a great deal of knowledge but very little understanding.
I don't think this will come up, though, since the Andromeda crew presumably wouldn't know about the Leviathans or the Catalyst.
Why does everyone think we are going to take people's home? We are civilized. Far more than the euros back in the day.
Yeah, and I can't imagine Bioware forcing us into a villain role, which is what we would be if we were conquering people's homes. I suspect we'll find that there are inhabitable worlds without much sapient life where we can settle, but some hostile group of aliens from other planets will want to attack us for other reasons.
As for how non-humans are involved, I am guessing that this is a multi-species mission. Honestly, if somebody in the Milky Way were to invent a ship capable of intergalactic travel and cryosleep, I'd bet on the asari or the salarians getting there before humans.