This thread makes for an interesting read. Getting on to the concerns surrounding the game and the exploration angle. It may not be so bad. I think it opens the possibilities up and as was mentioned BioWare is not usually so forthcoming in their storylines pre release anyway.
I like having the LI options regardless I think they can add depth to a story and, well, people are who they are regardless of societies hang ups (more power too them). Some of us even like ourselves and find it more interesting to see ourselves in the story than create an ideal that we think would fit the traditional hero. There should be more of us.
Last attempts at any kind of multiplayer for ME were failures and the exclusion of competitive multiplayer in this regard I think is a good thing. I would love the addition of cooperative game play, this is were I start getting booed, I have a love/hate relationship with Bungie's Destiny (as I am sure many of you may be in the closet about) but if BioWare can weave there story telling prowess with that style of cooperative play I think I would spend a few years and a few bucks on this game as well.
As for a fear, I think they will try to have a large scale coop game that if it does not integrate well, with the story telling, will epically fail. A fear I think is validated by the overwhelming popularity of games like Destiny, and several other MMOs. To ignore that and not include something in that area could result in a much smaller demographic for them. It may miss corporate financial goals that will limit future projects. They have to play for the blockbuster to live up to their previous titles and the industry in large part has moved on to coop interactive experiences for, as someone else commented and I'm sure I miss quote, "weirdos with friends."