Personally - I would prefer these games to NOT be built around combat. I know I'm talking to a wall, but I'd love my computer roleplaying games to evolve to catch up with several decades of tabletop where combat was not a requisite.
I would love an intense increase in non-combat mechanics.
You'd effectively be asking for Mass Effect to not be a TPS. If they're going that route, they'd be better off making a totally new sci-fi IP.
The reality is that Mass Effect is a shooter, so the player is going to be pretty good at killing stuff no matter what. It might be interesting to see a game react to the player's skill, but given that the player needs to be fairly proficient at the game's mechanics just to progress, I can't imagine how the game would make adequate distinctions in player skill or even why that would be an especial benefit to the game. As it is, being a trained military expert is just a convenient way of rationalizing the player's skill in lore.
Same goes for squadmates: BioWare could easily make them inexperienced, but that would only make them even more useless in combat than the already are, and it would be completely unreasonable story-wise to expect these greenhorns to accompany the player on dangerous combat missions in unexplored space.
I have to wonder what the premise of ME:A will be if we're apparently going to be "inexperienced." There's no way that we would be entrusted with the Tempest (presumably an advanced military ship) if we were noobies. I could easily imagine being "unrefined" maybe, but it just seems unreasonable to send untested soldiers on one of the most important–and sensitive if we're dealing with alien contact–jobs in the galaxy. I also don't envy the prospect of being labeled "inexperienced" if we're decent at shooters. It's just bound to cause more Tomb Raider-esque ludo-narrative dissonance or worse, more "I'm better than you no matter what," Kai Lengs.
Didn't we have some options like that in the first Mass Effect?
You had charm, intimidate, and hacking, but they rarely, if ever, helped the player circumvent combat. I'm all for alternate–especially nonviolent–approaches to combat scenarios, but Mass Effect isn't turning into a diplomacy simulator any time soon. If it did, I'd prefer that diplomacy was also navigated by player skill rather than stat checks because I think that would result in more engaging dialog, but that's only me.