<<<<<<<<<<(0)>>>>>>>>>>
The leaks and the interviews hint that humanity will be the underdog. Basically because their numbers compared to the "established space faring races" is insignificant. Add the other hint that deeper within the Andromeda galaxy there is a much stronger evil than the Khet and you have the road mapped out for the next story.
So, if the Andromeda story is done right, Ryder's success depends on her ability to make alliances with the locals. She has no choice, precisely due to their small numbers. Ryder and by proxy humanity's influence will only grow if the locals see the human spirit...( the tenacity, resolve, overcome obstacles, all the "goodness and apple pie") and bring disparate local governments together to fight off the Khet.
My simple interpretation is this. If the game sells well, we will see Andromeda 2-3.