Okay, now, sex happens, as the game acknowledges. And it happens between species. Normally, that would be that. But in the Mass Effect universe, the Asari can reproduce across species, which means there IS a way for two species to reproduce with each other. Now, there must certainly be at least some non-Asari trans-species relationships in the universe, and enough of these people must have money. And what's the one technology they'd all be willing to spend their fortunes on? Trans-species reproduction! And clearly it's not impossible, because the Asari do it! The trick is just finding a way to apply Asari reproduction to non-Asari.
I've though of two ways it could be done. The most realistic way seems to me to use the Asari as some kind of surrogate, esentially implanting an Asari egg with the genes of one of the parents in an Asari host (whatever species you want the kid to be, it would have to be that parent's DNA), and then the Asari has sex with the other parent. After a short period of time the embryo is removed (the Asari's immune system would likely attack the embryo) and grown externally.
The other way is to completely computerize it. The Asari's biology does something to get traits from the other parent into their kid. The problem with trans-species reproduction, even with compatible organs, is that they're not made to genetically go together: the kid wouldn't even grow, or at best be sterile (like ligers). The Asari have some kind of regular way of chosing those traits that wouldn't disrupt the viability of the child. If some kind of computer algorithm can be made to immitate this, it can be used to select genes from one parent, and combine them with another to make an egg from both parents (still primarily one species, since this is based on Asari biology).
I'm bringing this up because I know that if there was a biological block to humans of difference races having kids, people would be on that right now and working like lightning. Mass Effect 2 showed that at least the Quarians were getting around, so it seems like some company would be seeing dollar signs there. Also, the advantage is that gentically deficiant species like the Krogans can strengthen their genom with genes from outside species.
( Also, as a Tali fan, I have another agenda, but that's not relevant




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