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[Lancer159]

 Say Miranda dies in ME2 for your playthrough, I think its possible for her sister to be a squadmate in ME3, and Thane its his son, thanes going to die, ( his diseas thingy ) what about his kid for a squadmate? 

[Bravenu3]

Miranda's sister leads a normal life and Thane's dying wish will be that his son does NOT take the same path he did, so NO for both IMHO.