Well I must admit that I got a bit angry. The presentation looks to me as if they needed to justify all those stupid decisions they made. Especially the video comparing shooting in ME1 vs. ME2. That is simply lame. But now some comments.
InventoryWe all agree that in ME1, inventory was really unfortunate. Too many items without sorting. And too much loot which was mostly useless at the end. But still, I was always happy to find a Colossus or something as useful as this. The decision to remove it completely was unhappy as well. But what I really miss in ME2 is the possibility to change look of my companions. I think the best solution would be to have those lockers as in ME1 where you could change/update/customize armor for each squadmate. There does not have to be inventory or loot. They will have their armors in locker and you can obtain it by buying or by research perhaps. Regarding weapons. Am I the only one who was surprised that when you get that new pistol/SMG/sniper rifle by some miracle all squadmates have it? In the middle of a mission? They appeared from a thin air? Or what?
UpgradesNice try, but the ME1 system is still better. Moreover in ME2 you can upgrade damage up to 50% But 50% of what? What the hell is the basic damage? I am affraid even Bioware does not know

Not to mention ammo types made as skill. WTF? If today I want to load AP ammo, I just repeat in my mind AP ammo, AP ammo and boom, my rifle miraculously shoots AP rounds? I do not think so. So please, revert back to the ME1 model where we know what we are upgrading, how we are upgrading and what is the final effect.
AmmoYes, ammo, oh pardon, it is called heatsinks. The worst and most stupid change from ME1. If you wanted ammo, you should put it in in the ME1. Now it is nothing more than stupid. Show me any army which would willingly change unlimited ammo back to limited ammo. Every general proposing this would be removed as insane. And when speaking of ammo, it is universal right? So why the hell can not I use ammo from my shotgun in my sniper rifle. IT IS THE SAME. And no, I do not want to use the shotgun, I want to use the sniper rifle. I am an inflitrator. And finaly why do I have to run around like an idiot collecting ammo, oh sorry, heatsinks, when enemies and even my squadmates have unlimited ammo? Yes, in ME1 you could fire indefinitely at the end. But the same applied to enemies. So you should make enemies smarter to use this to their advantage, not to give them unlimited ammo while I have to run in front of their guns when I run out ammo for my weapons!
WeaponsThere really should be more variety. 2 or 3 pieces from each is not enough. Especially when there is no way for me to know the difference. Assault rifles have all the same description. There are not any stats (damage, rate of fire, nothing). And please give us the choice NOT TO take some wepons. Why do I have to run around encumbered by weapons as a Chritmas tree if I plan to use only one or two? All my companions in ME2 can carry only two weapons, why can not I?
ExplorationI like MAKO. Yes, it can be pain in the arse when you get stuck, but that is not a problem of the MAKO, but the lousy level design. And I like open space. Every side mission in ME1 was taking place on a large area where you could really use sniper rifles. Some planets like Virmire had so nice environment that everytime I was there I stopped and watched the ocean and the storm on the horizon (I bet every ME1 veteran did the same

). There is nothing like that in ME2. Not a single place you visit is memorable. Every mission is in closed corridor space. No exploration (and no, planet scanning is boring beyond believe, that is not an exploration), no planet surfaces, no open space, nothing. Just go straightforward and shoot whatever moves. And if it is too hard for you, we will place nice things to hide behind so you are NEVER surprised when ther is a fight coming.
So that is all what came on my mind watching that lame excuse. I am sorry, but ME1 is much better game for me. If ME2 was a standalone game with no connection to ME1, it would be perfect. But by completely changing the gender in a sequel, they made a terrible mistake and they will have to work hard to fix it in ME3. For me, I will not preorded ME3. I will wait and see what the game is like.