I'm just praying it isn't a full sequel to either Mass Effect or DAO, you people that want that are nuts and are not thinking properly. You think there were some issues with them this time, all you'd have is rushed out crap games if they announced and released full sequels in the next year.
Dragon Age took 4 plus years to develop, and ME 2 took a solid 27 months, and frankly, both could have used another 6 months or so to be absolutely everything they could have been. Not that they weren't great, but they could have been more. No chance for the quality we expect if a full sequel is announced with any release target in the next year.
I am hoping for an expansion to them though, and considering they both have mystery projects due around Q1 2011, that would be about right to put out a quality expansion around then.
A new IP would be good too, or JE 2, but not as good as a ME 2 expansion.
I just hope to hell it's not some lame crap like a website expanion or integration, or another lackluster handheld game. Not that those things don't have a place and all, but they sure don't deserve a countdown clock that builds up all this tension for all of us.